Life finally feels good for Peter Parker. He has managed to balance life as both Spider-Man and as Mary Jane's boyfriend. He is even planning on proposing to MJ. But life isn't always going to be easy for the webbed hero. Harry Osborn still hasn't forgiven Peter for the death of his father. He has developed the perfect technology and crowns himself the 'New Goblin'. Harry isn't the only problem. It is revealed that an escaped convict, Flint Marko is the real killer of Peter's uncle. After an accident, he is now the invincible 'Sandman', who has teamed up with Venom to target the superhero, who is struggling to handle his life.

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